中文摘要翻译成英文

Question

摘要
目的 应用患者自体CIK细胞回输治疗中晚期消化道肿瘤，并将疗效进行总结。方 法 用人工或机采的方法采集患者自体单个核细胞,淋巴细胞分离液离心分离诱导，激活,并大量扩增, 制备成CIK细胞, 静脉输注治疗中晚期恶性肿瘤患者158例。结 果 经培养后，CIK细胞扩增较好，达到预期质量标准，回输治疗后5例患者完全缓解, 14例患者部分缓解，117例病情稳定,25例进展,生命质量明显提高，治疗总疾病控制率为57.18%。治疗过程中除2例患者出现一过性发热(体温大约在37-380C之间),1例自觉关节疼痛 其它未发现任何不良反应。结 论 CIK治疗恶性消化道肿瘤安全可靠，副作用小,疗效确切,并能有效改善和提高患者的生存质量和临床症状。
关键词：CIK细胞;生物治疗;消化道肿瘤

Answer 1

摘要Abstract
目的：应用患者自体CIK细胞回输治疗中晚期消化道肿瘤，并将疗效进行总结。
Objective: use the back-infusion of patients’ autologous CIK cells in treatment of mid to late stage gastrointestinal tumor, and summarize the therapeutic effect.
方法：用人工或机采的方法采集患者自体单个核细胞，淋巴细胞分离液离心分离诱导，激活，并大量扩增，制备成CIK细胞，静脉输注治疗中晚期恶性肿瘤患者158例。
Methods: collect patients’ autologous mononuclear cells manually or by machine, then induce, activate and amplify them with lymphocyte separation liquid in centrifugal separation method to prepare the CIK cells, and inject into veins of patients of mid to late stage gastrointestinal tumor. 158 cases of therioma done.
结果：经培养后，CIK细胞扩增较好，达到预期质量标准，回输治疗后5例患者完全缓解，14例患者部分缓解，117例病情稳定，25例进展，生命质量明显提高，治疗总疾病控制率为57.18%。治疗过程中除2例患者出现一过性发热(体温大约在37-380C之间)，1例自觉关节疼痛，其它未发现任何不良反应。
Results: after cultivation, the CIK cells is well amplified and achieve the desired quality standards. After back-infusion treatment, 5 patients complete relieved, 14 partial relieved, 117 stabilized, 25 improved, quality of life for all patients improved, with a total disease control rate of 57.18%. Except the 2 cases in which 1 patient with pathergy fever (temperature between about 37-380C) and 1 patient with conscious joint pain in the course of treatment, all the others have no adverse reaction.
结论：CIK治疗恶性消化道肿瘤安全可靠，副作用小，疗效确切，并能有效改善和提高患者的生存质量和临床症状。
Conclusion: the CIK treatment for malignant gastrointestinal tumors are reliable with confirmed curative effect but little side effect, it effectively improve and enhance the quality of life and the clinical symptoms of patients.
关键词：CIK细胞；生物治疗；消化道肿瘤
Keywords: CIK cells; biological treatment; gastrointestinal tumor