第1个回答 2009-05-20
When did it start?
When did you begin to feel ill?
When did it begin?
When was the first time you had got this illness?
都可以！本回答被提问者采纳
第2个回答 2009-05-21
When did it occur/appear/begin/start?
When did you feel sick? or
When did you feel uncomfortable?
...
有多种表达法。
第3个回答 2009-05-20
When did it start?
When did you begin to feel ill?
第4个回答 2009-05-20
When did your disease begin?