这四个字表示的是数量，使用区别如下：
一、a few修饰可数名词，表示几个，是一个肯定陈述，意思是有一些。如：
I gave a dinner party for a few close friends.
我为几个密友办了晚宴。
We had a few drinks afterwards...
后来我们喝了几杯。
Here are a few more ideas to consider.
这儿还有几个想法可供考虑。
She was silent for a few seconds.
她沉默了几秒钟。
二、a little修饰
不可数名词，表示一点，是一个肯定陈述，意思也是有一些，如：
Mrs Caan needs a little help getting her groceries home.
卡安太太需要有人帮把手将食品杂货拿回家。
A little food would do us all some good.
吃点东西，对我们大家都会有好处。
a little light reading
一点消遣性的阅读
I shall be only a very little time.
我很快就好。
三、a lot of可以修饰可数名词或不可数名词，表示许多，用于肯定句。
A lot of our land is used to grow crops for export.
我们有很多土地被用来种植出口作物。
I remember a lot of things.
我记得很多事情。
'You'll find that everybody will try and help their colleague.' — 'Yeah. There's a lot of that.'
“你会发现同事们都会尽力互相帮助。”——“是呀，有很多这样的事。”
Lots of pubs like to deck themselves out with flowers in summer.
夏日里有许多酒吧喜欢用鲜花来装饰店面。
He drank lots of milk.
他喝了很多牛奶。
A lot of the play is very funny.
这出剧有许多地方都非常有趣。
四、some表示一些，可以修饰可数名词和不可数名词，用于肯定句。
Robin opened some champagne.
罗宾开了一些香槟。
Heat a couple of tablespoons of
olive oil, a chopped clove of garlic and some black pepper in a heavy saucepan.
将几勺橄榄油、一片切碎的蒜瓣和一些黑胡椒粉放入深平底锅里加热。
He went to fetch some books.
他去拿一些书来。
Some children refuse to eat at all and others overeat.
有些孩子根本不吃饭，另外的一些孩子却吃得过量。